In developmental studies, no adverse effects appeared in the offspring of pregnant rats who received eight times the recommended human dose {01}. Problems in humans have not been documented {01}. Safety and efficacy have not been established {01} in patients up to 18 years of age.

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Of those who had complete wart clearance at 10 weeks and could be followed for 12 additional weeks, 23% of patients remained wartfree {01}. Problems in humans have not been documented. Maternotoxicity, but not teratogenicity, as shown by reduced pup weights and delayed ossification, occurred in studies of female rats given doses 28 times the recommended human dose (based on mg per square meter of body surface area).

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Imiquimod potentially can exacerbate inflammatory conditions of the skin {01}. In one clinical trial that had a 4 to 6 ratio of females to males, 50% of patients, approximately 75% of females and 33% of males, experienced complete wart clearance after using imiquimod for 10 weeks (median, range 4 to 16 weeks). Of the remaining 50% of patients, 33% still had genital warts at 16 weeks and 17% withdrew from the clinical trial {01}.

Imiquimod is not a cure and new warts may develop during treatment; effect of imiquimod on transmission of genital warts is not known. Imiquimod does not have direct antiviral activity. Studies of mice show that imiquimod may induce cytokines, including interferonalpha, in mouse skin; clinical significance or relevance of this finding to humans is not known.

If covering is needed, patient should use nonocclusive material, such as cotton gauze or cotton underclothes. Patient should wash aldara drug category before and after administration to what is aldara cream for avoid translocation of cream, especially to eyes, and should wash the treatment area thoroughly with mild soap and water before engaging in sexual activities. Also, oils in the cream can weaken latex contraceptive devices, such as cervical caps, condoms, and diaphragms, and reduce their efficacy.

Protect from freezing. buy aldara in alabama material is provided for educational purposes only and is not to be used for medical advice, diagnosis or treatment. To view content sources and attributions, refer to our editorial policy.

When experiencing any discomfort or if severe reaction occurs, patient should delay next dose for several days, and report severe local skin reactions and rare systemic reactions to physician. Using nonocclusive dressing, such as gauze, or cotton underclothes to help manage skin reactions {01}. Treatment is continued aldara drug category wart is gone or for up to sixteen weeks.