No treatment related effects on embryofetal toxicity or teratogenicity were noted at 2 mg/kg/day (1. A combined fertility and periand postnatal development study was conducted in rats. Oral doses of 1, 1. This fetal effect was also noted in the oral rat embryofetal development study conducted with imiquimod. There are no adequate and wellcontrolled studies in pregnant women.

The overall median peak serum drug concentrations at the end of week 4 was between 0. Children aged 25 years received doses of 12. Children aged 612 years received doses of 12. No overall differences in safety or effectiveness were observed between these subjects and younger subjects. No other clinical experience has identified differences in responses between the elderly and younger subjects, but greater sensitivity of some older individuals cannot be ruled out.

The animal multiples of human exposure calculations were based on weekly aldara mg comparisons for the carcinogenicity studies described in this label. The animal multiples of human exposure calculations were based on daily dose comparisons for the reproductive toxicology studies described in this label. Systemic embryofetal development studies were conducted in rats and rabbits. Oral doses of 1, 5 and 20 mg/kg/day imiquimod were administered during the period of organogenesis (gestational days 6 15) to pregnant female rats. Intravenous doses of 0.

Safety and efficacy in patients with external genital/perianal warts below the age of 12 years have not price of aldara established. These aldara mg failed to demonstrate aldara mg. Similar to the studies conducted in adults, the most frequently reported adverse reaction from 2 studies in children with molluscum contagiosum was application order aldara cream online reaction. Erythema was the most frequently reported local skin reaction. The investigator determined the dose applied, either 1, 2 or 3 packets per dose, based on the size of the treatment area and the subject's weight.

An interruption of dosing should be considered. Patients should be warned to use protective clothing (e. Patients who may have considerable sun exposure, e. The enhancement of ultraviolet carcinogenicity is not necessarily dependent on phototoxic mechanisms. Therefore, patients should minimize or avoid natural or artificial sunlight exposure.